Application of Genomics for Identification of Systemic Toxicity Triggers Associated With VEGF-R Inhibitors

Volume: 23, Issue: 6, Pages: 1025 - 1033
Published: Jun 3, 2010
Abstract
The key to the discovery of new pharmaceuticals is to develop molecules that interact with the intended target and minimize interaction with unintended molecular targets, therefore minimizing toxicity. This is aided by the use of various in vitro selectivity assays that are used to select agents most potent for the desired target. Typically, molecules from similar chemical series, with similar in vitro potencies, are expected to yield comparable...
Paper Details
Title
Application of Genomics for Identification of Systemic Toxicity Triggers Associated With VEGF-R Inhibitors
Published Date
Jun 3, 2010
Volume
23
Issue
6
Pages
1025 - 1033
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.