Mathematical Model Identifies Blood Biomarker–Based Early Cancer Detection Strategies and Limitations
Abstract
Most clinical blood biomarkers lack the necessary sensitivity and specificity to reliably detect cancer at an early stage, when it is best treatable. It is not yet clear how early a clinical blood assay can be used to detect cancer or how biomarker-based strategies can be improved to enable earlier detection of smaller tumors. To address these issues, we developed a mathematical model describing dynamic plasma biomarker kinetics in relation to...
Paper Details
Title
Mathematical Model Identifies Blood Biomarker–Based Early Cancer Detection Strategies and Limitations
Published Date
Nov 16, 2011
Volume
3
Issue
109
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