Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus
Abstract
Bovine leukemia virus (BLV) and human T-cell leukemia virus type 1 (HTLV-1) make up a unique retrovirus family. Both viruses induce chronic lymphoproliferative diseases with BLV affecting the B-cell lineage and HTLV-1 affecting the T-cell lineage. The pathologies of BLV- and HTLV-induced infections are notably similar, with an absence of chronic viraemia and a long latency period. These viruses encode at least two regulatory proteins, namely,...
Paper Details
Title
Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus
Published Date
Jan 1, 2013
Journal
Volume
4
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