Differentiating maturational and aging-related changes of the cerebral cortex by use of thickness and signal intensity
Abstract
Cortical thickness decreases from childhood throughout life, as estimated by magnetic resonance imaging (MRI). This monotone trajectory does not reflect the fundamentally different neurobiological processes underlying morphometric changes in development versus aging. We hypothesized that intracortical gray matter (GM) and subjacent white matter (WM) T1-weighted signal intensity would distinguish developmental and age-related changes in the...
Paper Details
Title
Differentiating maturational and aging-related changes of the cerebral cortex by use of thickness and signal intensity
Published Date
Aug 1, 2010
Journal
Volume
52
Issue
1
Pages
172 - 185
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