Apoptosis, necrosis, or whatever: how to find out what really happens?

There is no doubt that thorough knowledge of apoptotic cell death is of paramount importance for many areas of current research. Despite many available ways of detecting apoptotic cell death, the analysis of apoptosis reveals considerable conceptual and technological problems. In this issue of The Journal of Pathology, Grogan and colleagues offer an interesting study, in which they present a promising model system for investigating the...