Overview of the interleukin-1 family of ligands and receptors

This issue of Seminars in Immunology on The Interleukin-1 (IL-1) Family of Ligands and Receptors updates the rapidly expanding importance of this family. There are individual chapters on IL-1α, IL-1β, processing and secretion of IL-1β, IL-18, IL-33, IL-36 and IL-37. In addition, a chapter of IL-1 decoy receptors, IL-1 signaling receptors and the clinical applications of IL-1 blockade in human disease is included. More than any other cytokine...