Biotechnological potential of plant-associated endophytic fungi: hope versus hype

•Fungal endophytes can produce a plethora of bioactive natural products. •Endophyte discoveries not yet translated into industrial bioprocesses. •Curiosity driven discoveries must be transformed into endophyte red biotechnology. •Develop sustainable strategies to harness endophyte-mediated pharma products. The potential of endophytes, particularly endophytic fungi, capable of demonstrating desirable functional traits worth exploitation using red...