Relation of body weight to development of ischemic heart disease in a cohort of young north American men after a 26 year observation period: The manitoba study

The role of overweight as a risk factor for ischemic heart disease remains controversial. Therefore, in the Manitoba Study of a cohort of 3,983 men with a mean age at entry of 30.8 years, initial measurements of body weight, represented by body mass index (weight/height2), were compared with the 26 year incidence of ischemic heart disease. After adjustment for the effects of age and blood pressure in univariate and multivariate analysis, body...