Organometallic compounds in oncology: implications of novel organotins as antitumor agents.
Abstract
Since the introduction of cisplatin in cancer therapy, metal complexes and organometallic compounds have been gaining growing importance in oncology. The impressive clinical effectiveness of cisplatin is limited by significant side effects and the emergence of drug resistance. Thus, novel classic and unconventional Pt(II) and Pt(IV) complexes have been introduced in therapy or are presently in advanced clinical trials. Moreover, innovative...
Paper Details
Title
Organometallic compounds in oncology: implications of novel organotins as antitumor agents.
Published Date
May 1, 2009
Journal
Volume
14
Issue
9
Pages
500 - 508
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Notes
History