Drug metabolism alterations in nonalcoholic fatty liver disease
Abstract
Drug-metabolizing enzymes play a vital role in the elimination of the majority of therapeutic drugs. The major organ involved in drug metabolism is the liver. Chronic liver diseases have been identified as a potential source of significant interindividual variation in metabolism. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the United States, affecting between 60 and 90 million Americans, yet the vast...
Paper Details
Title
Drug metabolism alterations in nonalcoholic fatty liver disease
Published Date
May 25, 2011
Journal
Volume
43
Issue
3
Pages
317 - 334
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