Review paper
Many levels of control of V gene rearrangement frequency
Abstract
Summary: V, D, and J gene segments rearrange at very different frequencies. As with most biological systems, there are multiple levels of control of V gene recombination frequency, and here we review some of the work from our laboratory that addresses these various control mechanisms. One of the important factors that affect non‐random V gene rearrangement frequency is the natural heterogeneity in recombination signal sequences (RSSs). Not only...
Paper Details
Title
Many levels of control of V gene rearrangement frequency
Published Date
Jul 9, 2004
Journal
Volume
200
Issue
1
Pages
44 - 56
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