Original paper

Lessons from high-throughput protein crystallization screening: 10 years of practical experience

Volume: 6, Issue: 5, Pages: 465 - 480
Published: Mar 22, 2011
Abstract
Introduction: X-ray crystallography provides the majority of our structural biological knowledge at a molecular level and, in terms of pharmaceutical design, is a valuable tool to accelerate discovery. It is the premier technique in the field, but its usefulness is significantly limited by the need to grow well-diffracting crystals. It is for this reason that high-throughput crystallization has become a key technology that has matured over the...
Paper Details
Title
Lessons from high-throughput protein crystallization screening: 10 years of practical experience
Published Date
Mar 22, 2011
Volume
6
Issue
5
Pages
465 - 480
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