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Measures of abdominal obesity assessed for visceral adiposity and relation to coronary risk

Published on Aug 1, 2004in International Journal of Obesity4.514
· DOI :10.1038/sj.ijo.0802695
Altan Onat41
Estimated H-index: 41
,
Günsel Ş. Avcı3
Estimated H-index: 3
+ 3 AuthorsVedat Sansoy24
Estimated H-index: 24
(Istanbul University)
Abstract
Measures of abdominal obesity assessed for visceral adiposity and relation to coronary risk
  • References (31)
  • Citations (255)
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References31
Newest
88 CitationsSource
#2Carl D. LangefeldH-Index: 77
Last. Richard N. BergmanH-Index: 96
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The relationship between insulin sensitivity and overall obesity is well established. However, there remains debate as to which of the fat depots, visceral abdominal tissue (VAT) or subcutaneous abdominal tissue (SAT), is of greater importance. Also, the relationship between fat distribution and insulin secretion is largely unknown. We studied S I , acute insulin response (AIR), and disposition index (DI), as obtained by minimal model analysis, in 999 Hispanic and 458 African-American men and wo...
253 CitationsSource
#1Barbara J. Nicklas (Wake Forest University)H-Index: 62
#2Brenda W.J.H. Penninx (Wake Forest University)H-Index: 134
Last. Karen E. Dennis (UCF: University of Central Florida)H-Index: 19
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OBJECTIVE —This study determined whether there is a critical level of visceral adipose tissue (VAT) associated with elevated coronary heart disease (CHD) risk factors in a cohort of women >45 years of age. RESEARCH DESIGN AND METHODS —Measurements of body composition (dual-energy X-ray absorptiometry), body fat distribution (computed tomography), fasting and 2-h postprandial (75-g) glucose concentrations, and fasting lipoprotein lipid and insulin concentrations were performed in 233 perimenopaus...
137 CitationsSource
and (3) supine resting blood pressure between groups who achieved these 2 distinct levels of VAT. Attainers showed a 2-fold greater loss of VAT compared to non-attainers (51.5% v 27.5%, P < .001). Attainers also showed a greater loss of body weight (19.0% v 12.5%, P < .01) and fat mass (34.8% v 18.4%, P < .001) after the program compared to non-attainers. Despite significant differences in the loss of total fat and VAT after the weight loss program, attainers and non-attainers showed comparable ...
48 CitationsSource
#1László B. Tankó (AAU: Aalborg University)H-Index: 38
#2Yu Z. Bagger (AAU: Aalborg University)H-Index: 27
Last. Claus Christiansen (AAU: Aalborg University)H-Index: 5
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Background— Although several lines of evidence point to an atherogenic role of central fat mass (CFM), few data are available to address the specific role played by peripheral fat mass (PFM). Methods and Results— This study was a cross-sectional analysis of 1356 women aged 60 to 85 years. Study variables were physical measures, CFM and PFM measured by DEXA, aortic calcification (AC) graded on lateral radiographs, lipid and glucose metabolites, blood pressure, and information on lifestyle factors...
235 CitationsSource
#1Scott M. GrundyH-Index: 171
#2Diane M. BeckerH-Index: 51
Last. Linda Van HornH-Index: 78
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10.7k Citations
#1Altan OnatH-Index: 41
#2Köksal CeyhanH-Index: 13
Last. Vedat Sansoy (Istanbul University)H-Index: 24
view all 6 authors...
The prevalence and the excess coronary heart disease (CHD) risk of the metabolic syndrome (MS) and its components were investigated in the Turkish Adult Risk Factor Study in both a prospective and a cross-sectional manner. In a population sample, representative of Turkish adults who have low levels of high- and low-density lipoprotein-cholesterol (HDL-C and LDL-C), MS was identified in conformity with the definition used in the recent NCEP guidelines. Prospective analysis was based on 2398 men a...
291 CitationsSource
#1Thang S. HanH-Index: 48
#2Ken Williams (University of Texas Health Science Center at San Antonio)H-Index: 33
Last. Steven M. Haffner (University of Texas Health Science Center at San Antonio)H-Index: 1
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Objective: To use standardized cut-offs of body mass index (BMI), waist circumference, waist-to-hip ratio, and fasting insulin levels to predict the development of metabolic disorders and metabolic syndrome. Research Methods and Procedures: We performed an 8-year follow-up study of 628 non-Hispanic whites and 1340 Mexican Americans, ages 25 to 64 years, from the second cohort of the San Antonio Heart Study. We defined metabolic disorders as dyslipidemia (triglycerides ≥2.26 mM or high-density li...
168 CitationsSource
#1Hanna-Maaria LakkaH-Index: 26
#2Timo A. LakkaH-Index: 80
Last. Jukka T. SalonenH-Index: 25
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Aims The purpose of the study was to investigate the associations of abdominal obesity and overall obesity with the risk of acute coronary events. Methods and Results Body mass index indicating overall obesity and waist-to-hip ratio and waist circumference indicating abdominal obesity were measured for 1346 Finnish men aged 42–60 years who had neither cardiovascular disease nor cancer at baseline. There were 123 acute coronary events during an average follow-up of 10·6 years. In Cox regression a...
335 CitationsSource
#1A. Hernández-Ono (Mexican Social Security Institute)H-Index: 3
#2G. Monter-Carreola (Mexican Social Security Institute)H-Index: 1
Last. Carlos Posadas-RomeroH-Index: 26
view all 7 authors...
OBJECTIVE: To investigate in a population-based random sample of postmenopausal women the adjusted association of visceral adipose tissue (VAT) with coronary risk factors. DESIGN: Cross-sectional population-based random sample study. SUBJECTS: Ninety-eight postmenopausal women (age 50-65y). MEASUREMENTS: Visceral and subcutaneous fat areas by computer axial tomography, anthropometry, lipid profile, fasting glucose and insulin, diet, physical activity, smoking status and alcohol intake. RESULTS: ...
57 CitationsSource
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#1Kashif Shaikh (Creighton University)H-Index: 1
Last. Mathew Budoff (UCLA: University of California, Los Angeles)H-Index: 3
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OBJECTIVE: Recent results from the Cardiovascular Trial of the Testosterone Trials showed that testosterone treatment of older men with low testosterone was associated with greater progression of noncalcified plaque (NCP). We evaluated the effect of anthropometric measures and cardiovascular biomarkers on plaque progression in individuals in the Testosterone Trial. METHODS: The Cardiovascular part of the trial included 170 men aged 65 years or older with low testosterone. Participants received t...
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Background Lipid accumulation product (LAP) and visceral adiposity index (VAI) are surrogates for visceral adiposity dysfunction. Our aim was to evaluate potential association of these two indices with the incidence of renal function decline.
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Last. Zbigniew Baj (Medical University of Łódź)H-Index: 16
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AbstractObjective: Obesity is responsible for a large proportion of the total burden of diseases in Europe. The aim of this study was to compare classic anthropometric parameters with new obesity-r...
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Abstract Purpose The transition to college is a vulnerable period for weight gain and the onset of obesity. Gut microbes differ in obese compared with lean individuals, but gut microbiota in adolescent-aged college freshmen during a known period of weight gain have never been studied. This pre–post observational pilot study assessed associations between intestinal microbiota changes and weight-related outcomes in healthy adolescent college freshmen living in on-campus dormitories at Arizona Stat...
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Last. Xiaoke Zhang (GW: George Washington University)H-Index: 6
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Body composition can be assessed in many different ways. High-end medical equipment, such as Dualenergy X-ray Absorptiometry (DXA), Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), offers high-fidelity pixel/voxel-level assessment but is prohibitive in cost. In the case of DXA and CT, the approach exposes users to ionizing radiation. Whole-body air displacement plethysmography (BOD POD) can accurately estimate body density, but the assessment is limited to the whole-body fat percen...
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#1Susan Park (KNU: Kyungpook National University)H-Index: 2
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Last. Jin-Won Kwon (KNU: Kyungpook National University)H-Index: 15
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This study investigated the sex-specific incidence of asthma and the effects of modifiable risk factors, particularly obesity, on asthma incidence among middle-aged and older individuals in Korea. We used data from the National Health Insurance Service-Health Screening Cohort (NHIS-HEALS), which includes health examinees aged 40–79 years in 2002–2003. In total, 459,529 participants with baseline anthropometric measurements were followed-up for 10 years and the development of asthma was evaluated...
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#1Wankyo Chung (SNU: Seoul National University)H-Index: 3
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Last. Jorge L. Gonzalez-Calvin (UGR: University of Granada)H-Index: 10
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Abstract Aim The association of non-alcoholic fatty liver disease (NAFLD) with insulin resistance (IR) is well established, yet little is known of their possible relationship with intrahepatic iron and serum tumour necrosis factor (TNF)-α concentrations in adults without diabetes. Thus, this study looked at the relationship of intrahepatic iron and serum TNF-α with intrahepatic triglycerides and IR in non-diabetic adults. Methods In this cross-sectional study of 104 healthy non-diabetic Caucasia...
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#1Atsushi Nakagomi (Chiba University)H-Index: 4
#2Yuko SunamiH-Index: 1
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Abstract Aims To investigate the predictive capability of insulin resistance surrogate markers for insulin resistance and arterial stiffness based on sex. Methods We assessed the association of triglyceride glucose (TyG) index, triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C), visceral adiposity index (VAI), and lipid accumulation product (LAP) with homeostasis model assessment-insulin resistance (HOMA-IR) and brachial–ankle pulse wave velocity (baPWV) in both sexes. Results...
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