Recombinant Thyrotropin in the Diagnosis of Congenital Hypothyroidism

Context: A modern approach to congenital hypothyroidism requires a definitive diagnosis of the underlying mechanisms; this can be achieved within the first weeks of life. When uncertainty persists, treatment is commenced, and the definitive diagnosis of congenital hypothyroidism is deferred to the age of 3 yr. Objectives: The interruption of thyroid replacement treatment is perceived as risky by parents and physicians. The aim of this pilot...