Association between obesity and vulnerability and serologic response to influenza vaccination in older adults

Serologic response to influenza vaccination declines with age. Few other host factors are known to be associated with serologic response. Our objective was to determine whether obesity and vulnerability independently predicted serologic response to influenza vaccination. Adults ≥50 years were recruited during the 2008–2009 influenza season. Subjects provided pre- and post-vaccination sera for measuring antibody titers to 2008–2009 vaccine...