Metal ions as inflammatory initiators of osteolysis
Volume: 135, Issue: 5, Pages: 683 - 695
Published: Mar 21, 2015
Abstract
Osteolysis and aseptic loosening currently contribute 75 % of implant failures. Furthermore, with over four million joint replacements projected to be performed in the United States annually, osteolysis and aseptic loosening may continue to pose a significant morbidity. This paper reviews the osteolysis cascade leading to osteoclast activation and bone resorption at the biochemical level. Additionally, the metal ion release mechanism from...
Paper Details
Title
Metal ions as inflammatory initiators of osteolysis
Published Date
Mar 21, 2015
Volume
135
Issue
5
Pages
683 - 695
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