A non-surgical method for induction of lung cancer in Wistar rats using a combination of NNK and high dietary fats
Abstract
Lung cancer is one of the most common malignant neoplasms all over the world. Smoking and a number of constituents of tobacco are responsible for development of lung tumours; however, the deleterious effects of tobacco-derived carcinogen, nitrosamine 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (nicotine-derived nitrosamine ketone (NNK)) remain unmatched. We report the development of a novel rodent model by administering multiple doses of NNK...
Paper Details
Title
A non-surgical method for induction of lung cancer in Wistar rats using a combination of NNK and high dietary fats
Published Date
Jan 13, 2013
Journal
Volume
250
Issue
4
Pages
919 - 929
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