Crystal Structure of Glycoprotein B from Herpes Simplex Virus 1
Abstract
Glycoprotein B (gB) is the most conserved component of the complex cell-entry machinery of herpes viruses. A crystal structure of the gB ectodomain from herpes simplex virus type 1 reveals a multidomain trimer with unexpected homology to glycoprotein G from vesicular stomatitis virus (VSV G). An alpha-helical coiled-coil core relates gB to class I viral membrane fusion glycoproteins; two extended beta hairpins with hydrophobic tips, homologous...
Paper Details
Title
Crystal Structure of Glycoprotein B from Herpes Simplex Virus 1
Published Date
Jul 14, 2006
Journal
Volume
313
Issue
5784
Pages
217 - 220
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