Predictive biomarker validation in practice: lessons from real trials
Abstract
With the advent of targeted therapies, biomarkers provide a promising means of individualizing therapy through an integrated approach to prediction using the genetic makeup of the disease and the genotype of the patient. Biomarker validation has therefore become a central topic of discussion in the field of medicine, primarily due to the changing landscape of therapies for treatment of a disease and these therapies purported mechanism(s) of...
Paper Details
Title
Predictive biomarker validation in practice: lessons from real trials
Published Date
Apr 14, 2010
Journal
Volume
7
Issue
5
Pages
567 - 573
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History