Parkinson's disease and local atrophy in subcortical nuclei: insight from shape analysis
Abstract
Parkinson's disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra pars compacta, inducing dopaminergic depletion in the striatum. Recently, subcortical nuclei shape analysis based on T1 imaging has been used in PD pathology. The present study aimed to test the hypothesis that changes in local volume detectable with T1-weighted imaging are concomitant with PD and may be used as biomarkers. We compared 21 PD...
Paper Details
Title
Parkinson's disease and local atrophy in subcortical nuclei: insight from shape analysis
Published Date
Jan 1, 2015
Journal
Volume
36
Issue
1
Pages
424 - 433
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