Cholinergic Augmentation Modulates Visual Task Performance in Sleep-Deprived Young Adults
Abstract
Using 24 h of total sleep deprivation to perturb normal cognitive function, we conducted a double-blind, placebo-controlled crossover study to evaluate the effect of the acetylcholinesterase inhibitor, donepezil, on behavioral performance and task-related brain activation in 28 healthy, young, adult volunteers. The behavioral tasks involved the parametric manipulation of visual short-term memory load and perceptual load in separate experiments...
Paper Details
Title
Cholinergic Augmentation Modulates Visual Task Performance in Sleep-Deprived Young Adults
Published Date
Oct 29, 2008
Journal
Volume
28
Issue
44
Pages
11369 - 11377
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