Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance Genes
Abstract
Emerging antibiotic resistance threatens human health. Gut microbes are an epidemiologically important reservoir of resistance genes (resistome), yet prior studies indicate that the true diversity of gut-associated resistomes has been underestimated. To deeply characterize the pediatric gut-associated resistome, we created metagenomic recombinant libraries in an Escherichia coli host using fecal DNA from 22 healthy infants and children (most...
Paper Details
Title
Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance Genes
Published Date
Nov 13, 2013
Journal
Volume
8
Issue
11
Pages
e78822 - e78822
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