Robust Score Statistics for QTL Linkage Analysis
Abstract
The traditional variance components approach for quantitative trait locus (QTL) linkage analysis is sensitive to violations of normality and fails for selected sampling schemes. Recently, a number of new methods have been developed for QTL mapping in humans. Most of the new methods are based on score statistics or regression-based statistics and are expected to be relatively robust to non-normality of the trait distribution and also to selected...
Paper Details
Title
Robust Score Statistics for QTL Linkage Analysis
Published Date
Mar 1, 2008
Volume
82
Issue
3
Pages
567 - 582
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