Induction of monooxygenase and transferase activities in rat by dietary administration of flavonoids.
Abstract
1. The influence of the dietary flavonoids, chrysin, quercetin, tangeretin, flavone and flavanone, on the components of the rat liver drug-metabolizing enzyme system was examined and compared with two well-known synthetic flavonoids 7,8-benzoflavone and 5,6-benzoflavone. 2. Polyhydroxylated molecules such as quercetin and chrysin, produced no significant changes on phase I and phase II enzyme activities. 3. Flavone was the most potent inducer,...
Paper Details
Title
Induction of monooxygenase and transferase activities in rat by dietary administration of flavonoids.
Published Date
Dec 1, 1989
Journal
Volume
19
Issue
12
Pages
1379 - 1386
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Notes
History