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Sample size of 12 per group rule of thumb for a pilot study
Abstract
When designing a clinical trial an appropriate justification for the sample size should be provided in the protocol. However, there are a number of settings when undertaking a pilot trial when there is no prior information to base a sample size on. For such pilot studies the recommendation is a sample size of 12 per group. The justifications for this sample size are based on rationale about feasibility; precision about the mean and variance; and...
Paper Details
Title
Sample size of 12 per group rule of thumb for a pilot study
Published Date
Oct 1, 2005
Journal
Volume
4
Issue
4
Pages
287 - 291
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Notes
History