Generalized Dowling-Degos disease

Dowling-Degos disease (DDD) is a rare inherited disease characterized by reticular hyperpigmentation on flexor surfaces.We sought to describe several cases of generalized DDD, a presentation that resemble dyschromatosis universalis hereditaria.The clinical manifestations, histopathologic, and genetic studies of a family with autosomal dominant inheritance were analyzed.The father and his sister had reticular hyperpigmentation on flexor surfaces,...