Induction of tumor stem cell differentiation—novel strategy to overcome therapy resistance in gastric cancer

Volume: 398, Issue: 4, Pages: 603 - 608
Published: Feb 15, 2013
Abstract
Purpose Metastases are a frequent finding in gastric cancer and are associated with poor prognosis. A recently discovered link between metabolic changes, differentiation, and therapy resistance due to tumor stem cells could depict a novel approach in cancer research and therapy. Phosphoglycerate kinase 1 (PGK1) is a metabolic enzyme and is known to be involved in enabling gastric cancer cells to be invasive and to disseminate. In this study, we...
Paper Details
Title
Induction of tumor stem cell differentiation—novel strategy to overcome therapy resistance in gastric cancer
Published Date
Feb 15, 2013
Volume
398
Issue
4
Pages
603 - 608
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