A Genetic Risk Variant for Myocardial Infarction on Chromosome 6p24 Is Associated With Impaired Central Hemodynamic Indexes

Volume: 25, Issue: 7, Pages: 797 - 803
Published: Jul 1, 2012
Abstract
Genome-wide association studies (GWAS) have identified novel variants associated with myocardial infarction (MI) in Caucasians. We hypothesized that those variants whose mechanism of risk is currently unknown, confer risk via pathways mediating arterial wave reflections which is an increasingly recognized risk factor for cardiovascular disease.Single-nucleotide polymorphisms (SNPs) at eight MI risk loci were genotyped and correlated with...
Paper Details
Title
A Genetic Risk Variant for Myocardial Infarction on Chromosome 6p24 Is Associated With Impaired Central Hemodynamic Indexes
Published Date
Jul 1, 2012
Volume
25
Issue
7
Pages
797 - 803
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