In vivo visualization of myelin water in brain by magnetic resonance
Abstract
We exploit the intrinsic difference in magnetic resonance spin-spin relaxation time, T2, between water associated with myelin sheaths and water in other central nervous system tissue in order to measure myelin water content within any region of an image or to generate indirectly a myelin map of the brain. In normal volunteers, myelin water maps give the expected myelin distribution. In multiple sclerosis patients, lesions exhibit different...
Paper Details
Title
In vivo visualization of myelin water in brain by magnetic resonance
Published Date
Jun 1, 1994
Volume
31
Issue
6
Pages
673 - 677
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