Inhibition of Cell Proliferation and Antitumor Activity of a Novel Organotin Compound
Volume: 20, Issue: 4, Pages: 10 - 10
Published: Jan 1, 2001
Abstract
Organotin compounds showed more antineoplastic effect against P388 leukemia in mice than any other class of compounds. However, they have not received as much attention as the platinum compounds. The present compound, Et2SnCl2.L [L = N-(2-pyridylmethylene)-4-toluidine] (OTC), showed an Sn-N bond length of 2.46 A which, because it is bigger than 2.39 A, is expected to achieve better formation of tin-DNA complexes. We previously reported on the...
Paper Details
Title
Inhibition of Cell Proliferation and Antitumor Activity of a Novel Organotin Compound
Published Date
Jan 1, 2001
Volume
20
Issue
4
Pages
10 - 10
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