Investigation of antimutagenic potential ofFoeniculum vulgareessential oil on cyclophosphamide induced genotoxicity and oxidative stress in mice
Abstract
The present study investigated the protective effects of Foeniculum vulgare (fennel) essential oil (FEO) against genotoxicity induced by cyclophosphamide (CP). Mice bone marrow chromosomal aberration (CA), micronucleus, and sperm abnormality assays were employed to measure genotoxicity and cytotoxicity, respectively. The activities of superoxide dismutase (SOD), glutathione (GSH), catalase (CAT), and malondialdehyde (MDA) content in the liver...
Paper Details
Title
Investigation of antimutagenic potential ofFoeniculum vulgareessential oil on cyclophosphamide induced genotoxicity and oxidative stress in mice
Published Date
Jan 21, 2012
Journal
Volume
36
Issue
1
Pages
35 - 41
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