Efficacy of Adalimumab as a long term maintenance therapy in ulcerative colitis

Introduction: Adalimumab is a recombinant human IgG1 monoclonal antibody to TNF-alpha. There are limited data with regard to its efficacy in ulcerative colitis. We report experience of adalimumab in ulcerative colitis in a single centre with a focus on the ability of this agent to maintain response and avoid colectomy in the medium to long-term. Methods: Twenty-three ulcerative colitis patients (mean age 32 years; 7 female) who received...