Role of Mechanotransduction in Vascular Biology: Focus on Thoracic Aortic Aneurysms and Dissections
Abstract
Thoracic aortic diseases that involve progressive enlargement, acute dissection, or rupture are influenced by the hemodynamic loads and mechanical properties of the wall. We have only limited understanding, however, of the mechanobiological processes that lead to these potentially lethal conditions. Homeostasis requires that intramural cells sense their local chemomechanical environment and establish, maintain, remodel, or repair the...
Paper Details
Title
Role of Mechanotransduction in Vascular Biology: Focus on Thoracic Aortic Aneurysms and Dissections
Published Date
Apr 10, 2015
Journal
Volume
116
Issue
8
Pages
1448 - 1461
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