Elucidation of Cellular Mechanisms Involved in Experimental Paromomycin Resistance in Leishmania donovani

Volume: 58, Issue: 5, Pages: 2580 - 2585
Published: May 1, 2014
Abstract
Leishmania donovani is the causative agent of the potentially fatal disease visceral leishmaniasis (VL). Chemotherapeutic options available to treat VL are limited and often face parasite resistance, inconsistent efficacy, and toxic side effects. Paromomycin (PMM) was recently introduced to treat VL as a monotherapy and in combination therapy. It is vital to understand the mechanisms of PMM resistance to safeguard the drug. In the present study,...
Paper Details
Title
Elucidation of Cellular Mechanisms Involved in Experimental Paromomycin Resistance in Leishmania donovani
Published Date
May 1, 2014
Volume
58
Issue
5
Pages
2580 - 2585
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