Subjective cognitive complaints and longitudinal changes in memory and brain function.

Subjective cognitive complaints are often used in the diagnosis of memory and other cognitive impairment. This study examined whether cognitive complaints are associated with longitudinal changes in cognition and cross-sectional differences in regional brain function during memory performance in 98 participants with a mean age of 75.The Cognitive Failures Questionnaire (CFQ) assessed cognitive complaints and mixed effects regression models were...