DEVELOPMENT OF AN IN VIVO BIOASSAY METHOD FOR PRIMARY PREVENTIVE SUBSTANCES OF THE METABOLIC SYNDROME – EFFECT OF KINGINKA‐CHA

1 We discovered a phenomenon in which the blood flow of vein microcirculation markedly decreased in the pathology of metabolic syndrome using a model of SHR/NDmcr-cp/cp (SHR/cp) rats. We tried to develop an in vivo assay method to search for substances for primary prevention of the metabolic syndrome using this blood flow decrease as a guide. 2 Using the assay method, we examined various teas that were expected to prevent the metabolic syndrome...