Neonatal monosodium glutamate treatment modifies glutamic acid decarboxylase activity during rat brain postnatal development
Abstract
Monosodium glutamate (MSG) produces neurodegeneration in several brain regions when it is administered to neonatal rats. From an early embryonic age to adulthood, GABA neurons appear to have functional glutamatergic receptors, which could convert them in an important target for excitotoxic neurodegeneration. Changes in the activity of the GABA synthesizing enzyme, glutamic acid decarboxylase (GAD), have been shown after different neuronal...
Paper Details
Title
Neonatal monosodium glutamate treatment modifies glutamic acid decarboxylase activity during rat brain postnatal development
Published Date
Mar 1, 2003
Journal
Volume
42
Issue
4
Pages
269 - 276
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