Induction of Heme Oxygenase‐1 mRNA and Protein in Neocortex and Cerebral Vessels in Alzheimer's Disease

: Previous studies demonstrated the specific association of heme oxygenase (HO)‐1 protein to the neurofibrillary pathology of Alzheimer's disease (AD). In this study, we used reverse transcription‐polymerase chain reaction methods to show the increased expression of HO‐1 but not HO‐2 mRNA transcripts in cerebral cortex and cerebral vessels from subjects with AD compared with age‐matched non‐AD controls. Neither the HO‐1 nor the HO‐2 mRNA level...