α-dystroglycan is a potential target of matrix metalloproteinase MMP-2
Abstract
Dystroglycan (DG) is a member of the glycoprotein complex associated to dystrophin and composed by two subunits, the β-DG, a transmembrane protein, and the α-DG, an extensively glycosylated extracellular protein. The β-DG ectodomain degradation by the matrix metallo-proteinases (i.e., MMP-2 and MMP-9) in both, pathological and physiological conditions, has been characterized in detail in previous publications. Since the amounts of α-DG and β-DG...
Paper Details
Title
α-dystroglycan is a potential target of matrix metalloproteinase MMP-2
Published Date
Jan 1, 2015
Journal
Volume
41
Pages
2 - 7
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