Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei
Abstract
The protozoan parasites Trypanosoma brucei spp. cause important human and livestock diseases in sub-Saharan Africa. In mammalian blood, two developmental forms of the parasite exist: proliferative 'slender' forms and arrested 'stumpy' forms that are responsible for transmission to tsetse flies. The slender to stumpy differentiation is a density-dependent response that resembles quorum sensing in microbial systems and is crucial for the parasite...
Paper Details
Title
Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei
Published Date
Dec 15, 2013
Journal
Volume
505
Issue
7485
Pages
681 - 685
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