Effect of flavanone on mixed-function oxidase and conjugation reactions in rats

1. Flavanone administered to female Fischer 344 rats (1.00mmol/kg per day for seven days) did not induce ethylmorphine demethylation, aniline hydroxylation, hexobarbital oxidation or aldrin epoxidation.2. Flavanone at 0.05mmol/kg per day for seven days increased glutathione-S- transferase activity with 1,2-dichloro-4-nitrobenzene and 1,2-epoxy-3-(p-nitrophenoxy) propane as substrates.3. Flavanone at 0.05 mmol/kg per day for seven days increased...