On the difficulty of increasing dental complexity

Nature64.80
Volume: 483, Issue: 7389, Pages: 324 - 327
Published: Mar 15, 2012
Abstract
Activation of EDA and activin A signalling, and inhibition of SHH signalling pathways together increase the number of cusps on cultured mouse cheek teeth, showing that a substantial increase in complexity requires multiple changes in developmental regulation. Mammalian cheek teeth, or molars, are a good example of a general phenomenon: the accumulation of complexity through evolution. In the laboratory, however, the trend seems to be in the...
Paper Details
Title
On the difficulty of increasing dental complexity
Published Date
Mar 15, 2012
Journal
Volume
483
Issue
7389
Pages
324 - 327
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