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Taking the STING out of cytosolic DNA sensing
Abstract
Detection of cytosolic DNA activates a downstream signaling molecule called STimulator of INterferon Genes (STING). Inappropriate or excessive activation of STING can lead to autoimmune disease. A new paper in Cell addresses the important question of how STING-dependent signaling is normally constrained. Detection of cytosolic DNA activates a downstream signaling molecule called STimulator of INterferon Genes (STING). Inappropriate or excessive...
Paper Details
Title
Taking the STING out of cytosolic DNA sensing
Published Date
Jan 1, 2014
Journal
Volume
35
Issue
1
Pages
1 - 2
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History