Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips
Abstract
Illumina’s Infinium HumanMethylation450 BeadChip arrays were used to examine genome-wide DNA methylation profiles in 22 sample pairs from colorectal cancer (CRC) and adjacent tissues and 19 colon tissue samples from cancer-free donors. We show that the methylation profiles of tumors and healthy tissue samples can be clearly distinguished from one another and that the main source of methylation variability is associated with disease status. We...
Paper Details
Title
Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips
Published Date
Sep 1, 2013
Journal
Volume
8
Issue
9
Pages
921 - 934
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