Solid state compatibility studies with tablet excipients using non thermal methods

Volume: 55, Issue: 3, Pages: 424 - 428
Published: Jun 1, 2011
Abstract
Compatibility between two new active pharmaceutical ingredients (API) and several pharmaceutical excipients used in solid formulations has been investigated by FT-IR and HPLC following storage under two different conditions. Compatibility was investigated by storage at isothermal stress conditions for (i) 3days and subsequently analysed by FT-IR and (ii) 12weeks of storage and analysis by HPLC. For the majority of the examined excipients a large...
Paper Details
Title
Solid state compatibility studies with tablet excipients using non thermal methods
Published Date
Jun 1, 2011
Volume
55
Issue
3
Pages
424 - 428
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