Match!

Adiposity as compared with physical activity in predicting mortality among women.

Published on Dec 23, 2004in The New England Journal of Medicine70.67
· DOI :10.1056/NEJMoa042135
Frank B. Hu202
Estimated H-index: 202
,
Barry M. Popkin318
Estimated H-index: 318
+ 3 AuthorsJoAnn E. Manson232
Estimated H-index: 232
Cite
Abstract
Background Whether higher levels of physical activity can counteract the elevated risk of death associated with adiposity is controversial. Methods We examined the associations of the body-mass index and physical activity with death among 116,564 women who, in 1976, were 30 to 55 years of age and free of known cardiovascular disease and cancer. Results During 24 years of follow-up, 10,282 deaths occurred — 2370 from cardiovascular disease, 5223 from cancer, and 2689 from other causes. Mortality rates increased monotonically with higher body-mass-index values among women who had never smoked (P for trend <0.001). In combined analyses of all participants, adiposity predicted a higher risk of death regardless of the level of physical activity. Higher levels of physical activity appeared to be beneficial at all levels of adiposity but did not eliminate the higher risk of death associated with obesity. As compared with women who were lean (i.e., they had a body-mass index lower than 25) and active (they spent ...
  • References (30)
  • Citations (698)
Cite
References30
Newest
#1Peter T. Katzmarzyk (Queen's University)H-Index: 81
#2Imke Janssen (Queen's University)H-Index: 30
Last.Chris I. ArdernH-Index: 26
view all 3 authors...
#1Mary Ellen Simpson (CDC: Centers for Disease Control and Prevention)H-Index: 1
#2Mary K. Serdula (CDC: Centers for Disease Control and Prevention)H-Index: 70
Last.Karin A. Mack (CDC: Centers for Disease Control and Prevention)H-Index: 30
view all 7 authors...
#1Katherine M. Flegal (CDC: Centers for Disease Control and Prevention)H-Index: 83
#2Margaret D. CarrollH-Index: 54
Last.Clifford L. JohnsonH-Index: 53
view all 4 authors...
Cited By698
Newest
#1Anne Lovise Nordstoga (NTNU: Norwegian University of Science and Technology)H-Index: 1
#2Ekaterina Zotcheva (NTNU: Norwegian University of Science and Technology)H-Index: 1
Last.Eivind Schjelderup Skarpsno (NTNU: Norwegian University of Science and Technology)H-Index: 2
view all 5 authors...
#1Cliodhna McHugh (Trinity College, Dublin)
#2Karen Hind (Durham University)H-Index: 11
Last.Fiona Wilson (Trinity College, Dublin)H-Index: 10
view all 4 authors...
#1Catherine Burton (University of the West of England)
#2Emily Doyle (University of the West of England)
Last.Shea Palmer (University of the West of England)H-Index: 17
view all 7 authors...
#1Jingjing Jiao (ZJU: Zhejiang University)
#2Gang Liu (Harvard University)H-Index: 16
Last.Qi Sun (Harvard University)H-Index: 62
view all 9 authors...
#1David Mizrahi (UNSW: University of New South Wales)H-Index: 4
#2Joanna E. Fardell (UNSW: University of New South Wales)H-Index: 13
Last.Richard J. Cohn (UNSW: University of New South Wales)H-Index: 27
view all 7 authors...
#1Gabriel M. Pagnotti (IUPUI: Indiana University – Purdue University Indianapolis)H-Index: 3
#2Gabriel M. Pagnotti (IUPUI: Indiana University – Purdue University Indianapolis)
Last.Clinton T. Rubin (SBU: Stony Brook University)H-Index: 68
view all 10 authors...
View next paperObesity as Compared With Physical Activity in Predicting Risk of Coronary Heart Disease in Women