Induction and regulation of pathogenic Th17 cell responses in schistosomiasis
Abstract
Schistosomiasis is a major tropical disease caused by trematode helminths in which the host mounts a pathogenic immune response against tissue-trapped parasite eggs. The immunopathology consists of egg antigen-specific CD4 T cell-mediated granulomatous inflammation that varies greatly in magnitude in humans and among mouse strains in an experimental model. New evidence, covered in this review, intimately ties the development of severe pathology...
Paper Details
Title
Induction and regulation of pathogenic Th17 cell responses in schistosomiasis
Published Date
Oct 25, 2012
Journal
Volume
34
Issue
6
Pages
873 - 888
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History