Genistein Suppression of TNF-α-induced Fractalkine Expression in Endothelial Cells
Abstract
Genistein is a polyphenolic nonsteroidal isoflavonoid with estrogen-like activity has been shown to have anticancer, antioxidant, and anti-inflammatory activities. Fractalkine is a unique chemokine that functions as a chemoattractant and an adhesion molecule on endothelial cells activated by proinflammatory cytokines. In this study, we investigated the effects of genistein (5-25 muM) on fractalkine expression in human umbilical vein endothelial...
Paper Details
Title
Genistein Suppression of TNF-α-induced Fractalkine Expression in Endothelial Cells
Published Date
Jan 1, 2010
Volume
26
Issue
3
Pages
431 - 440
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