Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy

Published on Jul 1, 2011in Intensive Care Medicine18.967
· DOI :10.1007/s00134-011-2231-3
David T. Selewski22
Estimated H-index: 22
(UM: University of Michigan),
Timothy T. Cornell20
Estimated H-index: 20
(UM: University of Michigan)
+ 7 AuthorsMichael Heung23
Estimated H-index: 23
(UM: University of Michigan)
Purpose In pediatric intensive care unit (PICU) patients, fluid overload (FO) at initiation of continuous renal replacement therapy (CRRT) has been reported to be an independent risk factor for mortality. Previous studies have calculated FO based on daily fluid balance during ICU admission, which is labor intensive and error prone. We hypothesized that a weight-based definition of FO at CRRT initiation would correlate with the fluid balance method and prove predictive of outcome.
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