Synthesis of 2-arylbenzothiazole derivatives and their application in bacterial detection

Volume: 22, Issue: 4, Pages: 1250 - 1261
Published: Feb 1, 2014
Abstract
A series of 2-arylbenzothiazole derivatives have been prepared as fluorogenic enzyme substrates in order to detect aminopeptidase, esterase, phosphatase and β-galactosidase activity in clinically important Gram-negative and Gram-positive bacteria. Substrates were incorporated into an agar-based culture medium and this allowed growth of intensely fluorescent bacterial colonies based on hydrolysis by specific enzymes. Substrate 20 targeted...
Paper Details
Title
Synthesis of 2-arylbenzothiazole derivatives and their application in bacterial detection
Published Date
Feb 1, 2014
Volume
22
Issue
4
Pages
1250 - 1261
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